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BIHAKUEN Hydroquinone cream

What is this leaflet:

This leaflet answers some common questions about the BIHAKUEN Hydroquinone cream preparation.
This product should be used under the advice of a doctor.

For proper treatment and better results, follow the information & guidelines provided in the leaflet.
Your doctor however, may prescribe a different course of treatment.

What is BIHAKUEN Hydroquinone cream used for:

BIHAKUEN Hydroquinone cream is applied to the skin for bleaching an lighting of the skin tone and skin pigmentation.
Topical application of hydroquinone produces a reversible depigmentation of the skin via inhibition of the enzymatic oxidation of tyrosine.

The selective inhibition of enzyme results in cessation of melanin formation and subsequently reduction in pigmentation.

Before you use BIHAKUEN Hydroquinone cream:

Do not use on broken skin. If pregnant or nursing consult a physician before use.

How to use BIHAKUEN Hydroquinone:

BIHAKUEN Hydroquinone cream is for external use only.
Apply a small amount of the cream on the skin in the affected area twice a day or as directed by a physician.

Message until fully absorbed into the skin.
BIHAKUEN Hydroquinone cream is recommended to be used during night hours as the product contains no sun blocking agent.

During the day avoid sun exposure by using a sunscreen or protective clothing over the affected areas.

Use of BIHAKUEN Hydroquinone cream should be discontinued after 3 months of treatment if no improvement is noticed.
There is no recommended dosage for pediatric patients under 12 years of age except under the advice an supervision of a physician.

INDICATION AND USAGE:

BIHAKUEN Hydroquinone cream is indicated for the gradual bleaching of hyperpigmented skin conditions such as chloasma, melasma, freckles, senile lentigines and other unwanted areas of melanin hyperpigmentation.

WARNINGS

Caution:

Hydroquinone is a skin bleaching agent which may produce unwanted cosmetic effects not used as directed.
The physician should be familiar with the contents of this insert before prescribing or dispensing this medication.

Test for skin sensitivity before using BIHAKUEN Hydroquinone cream by applying a small amount to an unbroken patch of skin an check in 24 hours.

Minor redness may not be harmful, but where there is itching or vesicle formation or excessive inflammatory response, further treatment is not advised.
Close patient supervision is recommended.

Contact with the eyes should be avoided.
In case of accidental contact, rinse your eyes thoroughly with water and contact a physician.

If no bleaching or lightening effect is noted after 3 months of treatment, the treatment should be discontinued

There are no sun blocking or sunscreening agents in BIHAKUEN Hydroquinone cream, and since minimal sunlight exposure may reverse the bleaching effect this preparation, it should be used at night or on areas of the body covered by protective clothing.
During daytime, sunscreen with SPF of 30 or higher or protective clothing should be used to prevent the bleached areas from repigmentation.

WARNING:

Contains sodium metabisulfite, a sulfite that may cause serious allergic type reactions (e.g., hives, itching, wheezing, anaphylaxis, serious asthma attacks)in certain people with sensitive skin.

PRECAUTIONS (See WARNINGS)

Pregnancy:

Animal reproduction studies have no been conducted with topical hydroquinone.

It is also not known whether hydroquinone can cause fetal harm when used topically on a pregnant woman or affect reproductive capacity.
It is not known to what degree, if any, topical hydroquinone is absorbed systemically.
If pregnant or nursing consult a physician before use.

Nursing Mothers:

It is not known whether topical hydroquinone is absorbed or excreted in human milk.
Consult a physician when topical hydroquinone is used by a nursing mother.

Pediatric Use:

Safety and effectiveness in pediatric patients below 12 years has not been established.

Persons Over age 65:

Clinical studies of hydroquinone in BIHAKUEN Hydroquinone cream did not include sufficient numbers of subjects aged 65 and over to determine whether they respond differently from younger subjects.

Other reported clinical experience has not identified differences in responses between the elderly and younger patients.
In general, dose selection for an elderly patient should be cautious, usually starting at the low end of the dosing range, reflecting the greater frequency of decreased hepatic, renal, or cardiac function, and of concomitant disease or other drug therapy.

ADVERSE REACTIONS:

No systemic adverse reactions have been reported.
Occasional hypersensitivity (localized contact dermatitis) may occur in which case the medication should be discontinued and the physician notified immediately.

OVERDOSAGE:

There have been no systemic reactions from the use of topical hydroquinone in BIHAKUEN Hydroquinone cream.

However, treatment should be limited to relatively small areas of the body at one time since some patients experience a transient skin reddening and a mild burning sensation which does not preclude treatment.

ACTIVE INGREDIENTS:

Hydroquinone, USP 4%.

OTHER INGREDIENTS :

Purified Water, Caprylic/Capric, C13-C14 Alkyl Benzoate, Cetyl Alcohol, Stearyl Alcohol, Cetearyl Alcohol, Ceteareth-20, Glyceryl Stearate, Lecithine, Glycerin, Sorbital, Barbadensis Leaf Juice (Aloe-Extract), Cucumis Sativus (Cucumber Extract), Methylparaben, Propylparaben Carbomer, Sodium Metabisulfite, Sodium Sulfate, Lactic Acid, Sodium Lauryl Sulfate, Ascorbyl Palmitate, Allantoin, Tocopheryl Acetate, BHT.

BIHAKUEN Hydroquinone cream should be stored at controlled room temperature 15-30℃ / 59-86゜F

KEEP THIS ALL DRUGS OUT OF THE REACH OF CHILDREN.

IN CASE OF ACCIDENTAL INGESTION, CALL A PHYSICIAN OR POISON CONTROL CENTER IMMEDIATELY.

Manufactured By:

Klein Anderson
San Diego, CA-USA

info@meddistributor.com
www.bihakuen.com

Made in USA